(Huntington Chorea; HD)
- Abnormal body movements
- Gradual deterioration or loss of intellectual abilities
- Behavior problems
- Sudden jerks or uncontrolled movements of the limbs or trunk
- Facial grimacing
- Continuous need to turn head and shift gaze
- Walking that is unsteady or dance-like
- Difficulty with eating and swallowing, which may result in weight loss
- Difficulty dressing, sitting, and caring for oneself
- Grunting or poor articulation of speech
- Trouble with attention and awareness
- Confusion or disorientation
- Loss of memory
- Loss of judgment
- Loss of ability to think rationally
- Irritability and moodiness
- Depression (common)
- Social withdrawal or antisocial behavior
- Irresponsible behavior
- Personality changes
- Psychosis—a severe emotional and behavioral disorder that often interferes with a person's ability to relate to others and to function in daily life
- Paranoia—a mental disorder that involves feelings of being watched, followed, or harmed by others
- Hallucinations—the perception of a thing or person that is not present
- Cause the loss of the physical and mental ability to care for oneself
- Cause severe disability, making full-time or nursing home care necessary
- Result in death, often due to a fall or pneumonia
|MRI Scan of the Brain|
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Hereditary Disease Foundation http://www.hdfoundation.org
Huntington Disease Society of America http://www.hdsa.org
Health Canada http://www.hc-sc.gc.ca
Huntington Society of Canada http://www.huntingtonsociety.ca
A physician's guide to the management of Huntington's disease. Huntington's Disease Society of America website. Available at: http://hdsa.org/wp-content/uploads/2015/03/PhysiciansGuide%5F3rd-Edition.pdf. Accessed September 30, 2014.
Fast facts about HD. Huntington's Disease Society of America website. Available at: http://hdsa.org/wp-content/uploads/2015/03/HDSA%5FFast-Facts.pdf?23ef42. Accessed September 30, 2014.
Frank S, Jankovic J. Advances in the pharmacological management of Huntington's disease. Drugs. 2010;70(5):561-571.
Huntington disease. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated August 11, 2014. Accessed September 30, 2014.
Mestre T, Ferreira J, Coelho MM, et al. Therapeutic interventions for symptomatic treatment in Huntington's disease. Cochrane Database Syst Rev. 2009;8(3):CD006456.
NINDS Huntington's disease information page. National Institute of Neurological Disorders and Stroke website. Available at: http://www.ninds.nih.gov/disorders/huntington/huntington.htm. Updated April 16, 2014. Accessed September 30, 2014.
Paulsen JS, Hoth KF, Nehl C, Stierman L. Critical periods of suicide risk in Huntington's disease. Am J Psychiatry. 2005;163(4):725-731.
9/3/2014 DynaMed's Systematic Literature Surveillance. Available at: http://www.ebscohost.com/dynamed: Wippold FJ, Brown DC, Broderick DF, et al. American College of Radiology (ACR) Appropriateness Criteria for dementia and movement disorders. Available at: http://www.acr.org/~/media/ACR/Documents/AppCriteria/Diagnostic/DementiaAndMovementDisorders.pdf. Updated 2014. Accessed September 30, 2014.
- Reviewer: Rimas Lukas, MD
- Review Date: 08/2015 -
- Update Date: 09/30/2014 -