(CFS; Chronic Fatigue and Immune Dysfunction Syndrome)
|Central Nervous System and Organs Including Endocrine Glands|
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- Unexplained, new onset, persistent fatigue that is not relieved with bed rest and often worsens with physical or mental activity
- Unexplained muscle aches
- Joint pain without swelling or redness over 6 months
- Headaches over 6 months
- Trouble with short-term memory or concentration a "brain fog"
- Forgetfulness or confusion
- Irritability, anxiety , panic attacks, mood swings, or depression
- Sore throat over 6 months
- Tender lymph nodes over 6 months
- Trouble sleeping or not feeling refreshed after sleep over 6 months
- Visual disturbances (eyes sensitive to light, blurring, pain)
- Reduced activities (social, job-related, educational, and personal)
- Lightheadedness, balance problems, or fainting
- Chills and night sweats
- Allergies or sensitivities to foods , chemicals, odors, medications, or noise
- Severe, chronic fatigue for at least 6 months that is not due to another illness or medical cause, along with:
At least 4 of the following symptoms according to the International Chronic Fatigue Syndrome Study Group Criteria:
- Impairment of short-term memory or concentration
- Sore throat
- Tender lymph nodes
- Muscle pain
- Joint pain without swelling or redness
- Headaches of a new type, severity, or pattern
- Unrefreshing sleep
- Prolonged fatigue lasting 24 hours or more after exercise
Diet and Nutrition
- Anti-anxiety drugs
- Over-the-counter medications like acetaminophen, aspirin, and ibuprofen to treat pain and fever
- Stimulants—mild ones may be helpful
- Sedatives—to help with insomnia
Centers for Disease Control and Prevention http://www.cdc.gov
Chronic Fatigue and Immune Dysfunction Syndrome Association of America http://www.cfids.org
Health Canada http://www.hc-sc.gc.ca
Women's Health Matters http://www.womenshealthmatters.ca
Chronic fatigue syndrome. American Academy of Family Physicians Family Doctor website. Available at: http://familydoctor.org/familydoctor/en/diseases-conditions/chronic-fatigue-syndrome.html. Updated November 2010. Accessed December 28, 2012.
Chronic fatigue syndrome. Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/cfs/index.html. Updated May 16, 2012. Accessed December 28, 2012.
Chronic fatigue syndrome. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated November 10, 2012. Accessed December 28, 2012.
Craig T, Kakumanu S. Chronic fatigue syndrome: evaluation and treatment. Am Fam Physician. 2002;65(6):1083-1090.
Darbishire L, Ridsdale L, et al. Distinguishing patients with chronic fatigue from those with chronic fatigue syndrome: a diagnostic study in UK primary care. Br J Gen Pract. 2003;53(491):441-445.
Prins JB, Bleijenberg G, et al. Cognitive behaviour therapy for chronic fatigue syndrome: a multicertre randomized controlled trial. Lancet. 2001;357(9259):841-847.
Reeves WC, Wagner D, et al. Chronic fatigue syndrome: A clinically empirical approach to its definition and study. BMC Medicine. 2005;3:19.
Reid S, Chalder T, et al. Chronic fatigue syndrome. Clin Evid. 2004;(12):1578-1593.
Rimes KA, Chalder T. Treatments for chronic fatigue syndrome. Occup Med. 2005;55:32-39.
3/3/2011 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed: White P, Goldsmith K, et al. Comparison of adaptive pacing therapy, cognitive behaviour therapy, graded exercise therapy, and specialist medical care for chronic fatigue syndrome (PACE): a randomised trial. Lancet. 2011;377(9768):823-826.
10/1/2013 DynaMed's Systematic Literature Surveillance http://www.ebscohost.com/dynamed: Patterson E, Wan YW, et al. Nonpharmacological nursing interventions for the management of patient fatigue: a literature review. J Clin Nurs. 2013;22(19-20):2668-2678.
- Reviewer: Marcin Chwistek, MD
- Review Date: 11/2014 -
- Update Date: 01/15/2014 -