What Is Melatonin and How Does It Work?
The Research on Melatonin for Sleep
Other Uses of Melatonin
What Are the Precautions?
Should You Try It?
Family Doctor—American Academy of Family Physicians http://familydoctor.org
National Institute of Mental Health http://www.nimh.nih.gov
Canadian Family Physician http://www.cfpc.ca
Health Canada http://www.hc-sc.gc.ca
Almeida Montes LG, Ontiveros Uribe MP, Cortes Sotres J, et al. Treatment of primary insomnia with melatonin: a double-blind, placebo-controlled, crossover study. J Psychiatry Neurosci. 2003;28:191-196.
Asayama K, Yamadera H, Ito T, et al. Double blind study of melatonin effects on the sleep-wake rhythm, cognitive and non-cognitive functions in Alzheimer type dementia. J Nippon Med Sch. 2003;70:334-341.
Fraschini F, Cesarani A, Alpini D, et al. Melatonin influences human balance. Biol Signals Recept. 1999;8:111-119.
Graw P, Werth E, Krauchi K, et al. Early morning melatonin administration impairs psychomotor vigilance. Behav Brain Res. 2001;121:167-172.
Insomnia in adults. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated October 5, 2015. Accessed November 4, 2015.
Kemp S, Biswas R, Neumann V, et al. The value of melatonin for sleep disorders occurring post-head injury: a pilot RCT. Brain Inj. 2004;18:911-919.
Melatonin. EBSCO Natural and Alternative Treatments website. Available at: https://www.ebscohost.com/academic/natural-alternative-treatments. Updated August 2013. Accessed November 4, 2015.
Melatonin and sleep. National Sleep Foundation website. Available at: http://www.sleepfoundation.org/article/sleep-topics/melatonin-and-sleep. Accessed November 4, 2015.
Melatonin for jet lag. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed. Updated June 2, 2010. Accessed November 4, 2015.
Nave R, Iani C, Herer P, et al. Residual effects of daytime administration of melatonin on performance relevant to flight. Behav Brain Res. 2002;131:87-95.
- Reviewer: Michael Woods, MD
- Review Date: 09/2015 -
- Update Date: 11/21/2013 -