What Is Typhoid?
- High fever, usually up to 103˚F or 104˚F
- Stomach pains
- Loss of appetite
What Is the Typhoid Vaccine?
- An inactivated vaccine that is injected
- A live, weakened vaccine given orally
Who Should Get Vaccinated and When?
- People who are traveling to areas outside the US where typhoid commonly exists
- People who are in close contact with an individual who has or carries typhoid
- People who work with the bacterium—typically laboratory workers
What Are the Risks Associated With the Typhoid Vaccine?
- Redness or swelling at injection site (inactivated only)
- Abdominal pain
- Nausea or vomiting
- Changes in behavior
- Extremely high fever
- Difficulty breathing, hoarse voice, and wheezing
- Pale skin
- Rapid heartbeat
Who Should Not Get Vaccinated?
For the shot, the following individuals should not get vaccinated. Those who:
- Have had a severe allergic reaction to a previous typhoid vaccine or any of its components
- Are under age 2 years
For the oral vaccine, the following individuals should not get vaccinated. Those who:
- Have had a severe allergic reaction to a previous typhoid vaccine or its components
- Are under age 6 years
- Are currently taking certain antibiotics
- Have a weakened immune systems, including HIV/AIDS
- Are being treated with drugs that can compromise the immune system, such as steroids
- Have cancer
- Are undergoing treatment for cancer with medication or radiation
What Other Ways Can Typhoid Be Prevented Besides Vaccination?
- Frequent and thorough hand washing, particularly before handling food
- Properly cleaning and preparing food to ensure no contamination
- Avoiding uncooked vegetables or fruit that cannot be peeled
- Boiling water before drinking or using
- Avoiding potentially contaminated food or water
What Happens in the Event of an Outbreak?
WHERE CAN I GET MORE INFORMATION?
Family Doctor—American Academy of Family Physicians http://familydoctor.org
US Centers for Disease Control and Prevention http://www.cdc.gov
Bhutta ZA, Khan MI, Soofi SB, Ochiai RL. New advances in typhoid Fever vaccination strategies. Adv Exp Med Biol. 2011;697:17-39.
Nelson CB, de Quadros C. Coalition against typhoid: a new, global initiative to advance typhoid vaccination. Vaccine. 2011;29(38):6443.
Typhoid vaccine. US Centers for Disease Control and Prevention website. Available at: http://www.cdc.gov/vaccines/hcp/vis/vis-statements/typhoid.pdf. Published May 29, 2012. Accessed June 10, 2015.
- Reviewer: David L. Horn, MD, FACP
- Review Date: 06/2015 -
- Update Date: 06/20/2014 -