What Is Chaparral Used for Today?
1 Ping YF, Yao XH, Chen JH, et al. The anti-cancer compound Nordy inhibits CXCR4-mediated production of IL-8 and VEGF by malignant human glioma cells. J Neurooncol. 2007 Apr 6. [Epub ahead of print]
2 Zavodovskaya M, Campbell MJ, Maddux BA, et al. Nordihydroguaiaretic acid (NDGA), an inhibitor of the HER2 and IGF-1 receptor tyrosine kinases, blocks the growth of HER2-overexpressing human breast cancer cells. J Cell Biochem. 2007 Jun 11. [Epub ahead of print]
3 Meyer GE, Chesler L, Liu D, et al. Nordihydroguaiaretic acid inhibits insulin-like growth factor signaling, growth, and survival in human neuroblastoma cells. J Cell Biochem. 2007 May 7. [Epub ahead of print]
4 Chen JH, Yao XH, Gong W, et al. A novel lipoxygenase inhibitor Nordy attenuates malignant human glioma cell responses to chemotactic and growth stimulating factors. J Neurooncol. 2007 Mar 22. [Epub ahead of print]
5 Sheikh NM, Philen RM, Love LA. Chaparral-associated hepatotoxicity. Arch Int Med. 1997;157:913-919.
6 Kauma H, Koskela R, Makisalo H, et al. Toxic acute hepatitis and hepatic fibrosis after consumption of chaparral tablets. Scand J Gastroenterol. 2004;39:1168-1171.
7 Brinker F. Larrea tridentata (D.C.) Coville (chaparral or creosote bush) [review]. Br J Phytother. 1993/1994;3:10-31.
8 McGuffin M, Hobbs C, Upton R, Goldberg A. American Herbal Products Association’s Botanical Safety Handbook. Boca Raton, FL: CRC Press; 1997: 67.
- Reviewer: EBSCO CAM Review Board
- Review Date: 09/2014 -
- Update Date: 09/18/2014 -