|Cross Section of Intestine With Villi|
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- Pain in the joints (in 90% of cases)
- Pain and bloating in the abdomen
- Fatty foul-smelling stools
- Bleeding from the intestines
- Weight loss
- Fatigue (often from anemia )
- Cough and chest pain
- Increased skin pigmentation (in 50% of cases)
- Swollen lymph glands
- Vitamins A, B12, D, E, and K
National Institute of Diabetes and Digestive and Kidney Diseases http://www.niddk.nih.gov
National Organization for Rare Disorders http://www.rarediseases.org
The Canadian Association of Gastroenterology (CAG) http://www.cag-acg.org
Health Canada http://www.hc-sc.gc.ca
Desnues B, Al Moussawi K, et al. New insights into Whipple's disease and Tropheryma whipplei infections. Microbes Infect . 2010;12(14-15):1102-1110.
Fenollar F, Nicoli F, et al. Progressive dementia associated with ataxia or obesity in patients with Tropheryma whipplei encephalitis. BMC Infect Dis . 2011;11:171.
Fenollar F, Trani M, et al. Prevalence of asymptomatic Tropheryma whipplei carriage among humans and nonhuman primates. J Infect Dis . 2008;197(6):880-887.
Whipple disease. EBSCO DynaMed website. Available at: https://dynamed.ebscohost.com/about/about-us . Updated December 28, 2010. Accessed January 8, 2013.
Whipple's disease. National Digestive Diseases Information Clearinghouse website. Available at: http://digestive.niddk.nih.gov/ddiseases/pubs/whipple/index.aspx . Updated April 30, 2012. Accessed January 8, 2013.
Whipple’s disease: a rare, insidious disorder with serious consequences. Drug and Therapy Perspectives . 1999;13:8-10.
- Reviewer: Daus Mahnke, MD
- Review Date: 09/2013 -
- Update Date: 09/30/2013 -