(Anemia of Inflammation; Hypoferremia of Inflammatory Disease; ACD)
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- Chronic infections, such as tuberculosis, lung abscess, and subacute endocarditis
- Noninfectious inflammatory diseases, such as rheumatoid arthritis, osteomyelitis, systemic lupus erythematosus, and inflammatory bowel disease
- Common childhood infections, including ear infections and urinary tract infections
- Heart failure, thyroid disease, and kidney failure
- Cancer, particularly Hodgkin’s disease, lung cancer, and breast cancer
- Pale complexion, lightheadedness, fatigue, and rapid heartbeat
- Blood tests
- A bone marrow biopsy
Iron Disorders Institute http://www.irondisorders.org
National Heart, Lung, and Blood Institute http://www.nhlbi.nih.gov
Canadian Cancer Society http://www.cancer.ca
Health Canada http://www.hc-sc.gc.ca
Beutler E. Unlocking the mysteries of iron homeostasis and of the anemia of chronic disease: is hepcidin the key? Blood. 2003;102:775.
Weiss G, Goodnough, LT. Anemia of chronic disease. NEJM. 2005;352:1011-1023.
What is anemia? National Heart Lung and Blood Institute website. Available at: http://www.nhlbi.nih.gov/health/health-topics/topics/anemia. Updated May 18, 2012. Accessed September 23, 2015.
3/12/2008 DynaMed Systematic Literature Surveillance http://www.ebscohost.com/dynamed: Bennett CL, Silver SM, Djulbegovic B, et al. Venous thromboembolism and mortality associated with recombinant erythropoietin and darbepoetin administration for the treatment of cancer-associated anemia. JAMA. 2008;299:914-924.
9/2/2009 DynaMed Systematic Literature Surveillance http://www.ebscohost.com/dynamed: Bohlius J, Schmidlin K, Brillant C, et al. Erythropoietin or Darbepoetin for patients with cancer—meta-analysis based on individual patient data. Cochrane Database Syst Rev. 2009;(3):CD007303.
- Reviewer: Marcin Chwistek, MD
- Review Date: 09/2015 -
- Update Date: 08/19/2014 -